Flow-independent nitric oxide exchange parameters in healthy adults
نویسندگان
چکیده
منابع مشابه
Flow-independent nitric oxide exchange parameters in healthy adults.
Currently accepted techniques utilize the plateau concentration of nitric oxide (NO) at a constant exhalation flow rate to characterize NO exchange, which cannot sufficiently distinguish airway and alveolar sources. Using nonlinear least squares regression and a two-compartment model, we recently described a new technique (Tsoukias et al. J Appl Physiol 91: 477-487, 2001), which utilizes a pree...
متن کاملFlow-independent nitric oxide exchange parameters in cystic fibrosis.
Exhaled nitric oxide (NO) remains a promising noninvasive index for monitoring inflammatory lung diseases; however, the plateau concentration (C(NO,plat)) is nonspecific and requires a constant exhalation flow rate. We utilized a new technique that employs a variable flow rate to estimate key flow-independent parameters characteristic of NO exchange in a group (n = 9) of 10 to 14 yr-old healthy...
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It is a well-known fact that smoking is associated with a reduction in exhaled nitric oxide (NO) levels. There is, however, limited knowledge relating to the smoking-induced changes in production or exchange of NO in different compartments of the airways. This study comprised 221 adult subjects from the European Community Respiratory Health Survey II, who were investigated in terms of their exh...
متن کاملIgE sensitisation in relation to flow-independent nitric oxide exchange parameters
BACKGROUND A positive association between IgE sensitisation and exhaled NO levels has been found in several studies, but there are no reports on the compartment of the lung that is responsible for the increase in exhaled NO levels seen in IgE-sensitised subjects. METHODS The present study comprised 288 adult subjects from the European Community Respiratory Health Survey II who were investigat...
متن کاملImpact of high-intensity exercise on nitric oxide exchange in healthy adults.
PURPOSE After exercise, exhaled NO concentration has been reported to decrease, remain unchanged, or increase. A more mechanistic understanding of NO exchange dynamics after exercise is needed to understand the relationship between exercise and NO exchange. METHODS We measured several flow-independent NO exchange parameters characteristic of airway and alveolar regions using a single breath m...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2001
ISSN: 8750-7587,1522-1601
DOI: 10.1152/jappl.2001.91.5.2173